Gastric Varices study: Non-selective beta blockers
Official title Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram Trial
ClinicalTrials.gov ID: NCT07168395
What this study is testing
What is Non-selective beta blockers?
Non-selective beta blockers is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for gastric varices.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A number of treatment modalities are currently in use for gastric variceal bleeding (GVB).
- Time commitment: about 2 years
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age \> 18 years
- Patients with compensated cirrhosis with a higher risk of decompensation based on AASLD 2023 Practice Guidance (Kaplan et al) - no ascites with...
- Confirmed diagnosis of gastric varices either through CT, MRI, or Endoscopy.
- No imaging (LIRAD4 or 5) or tumor marker (AFP) evidence of HCC or other malignancy
- MELD \< 20
You likely can't join if
- Age \<18 years
- Patients with decompensated cirrhosis based on AASLD 2023 Practice Guidance (Kaplan et al)
- Cardiac failure
- Active variceal bleeding
- History of gastroesophageal variceal bleeding
- Previous TIPS, BRTO, CARTO or PARTO procedure
See the full eligibility criteria
- Age \> 18 years
- Patients with compensated cirrhosis with a higher risk of decompensation based on AASLD 2023 Practice Guidance (Kaplan et al) - no ascites with endoscopic visualization of varices
- Confirmed diagnosis of gastric varices either through CT, MRI, or Endoscopy.
- No imaging (LIRAD4 or 5) or tumor marker (AFP) evidence of HCC or other malignancy
- MELD \< 20
- First de novo RTO procedure
- Taking NSBB
- Patent internal jugular or right common femoral vein
- Willing to provide the hepatology service information for F/U
- No known diagnosis of hypercoagulopathy
- Patent portal vein or portal vein cavernous transformation
- Age \<18 years
- Patients with decompensated cirrhosis based on AASLD 2023 Practice Guidance (Kaplan et al)
- Cardiac failure
- Active variceal bleeding
- History of gastroesophageal variceal bleeding
- Previous TIPS, BRTO, CARTO or PARTO procedure
- No right jugular or right common femoral venous access
- No portal vein flow
- Malignancy
- Life expectancy of less than 6 months
The study team makes the final eligibility decision.
Where it is enrolling
- Los Angeles, California, United States
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 2 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Los Angeles, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.