Clinical trial for Multiple Sclerosis
Official title Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis
ClinicalTrials.gov ID: NCT07174973
What this study is testing
- What it's testing
- The study wants to see whether adding electrical stimulation to balance training improves balance, walking, and brain‑spinal cord communication in people with multiple sclerosis.
- Who it's for
- It is looking for adults who have multiple sclerosis and have trouble walking or keeping their balance.
- What's involved
- Participants will do 12 supervised balance training sessions over 6 weeks, using interactive games while wearing a safety harness. Some will also receive electrical pulses to leg muscles (FES) or to the spinal cord through the skin (TSCS).
- Time commitment
- The study lasts about 6 weeks of training, with follow‑up visits 8 weeks after training to repeat balance and walking tests.
- Time commitment: about 6 weeks
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Confirmed diagnosis of Multiple Sclerosis (MS) according to the revised McDonald criteria
- Age ≤ 65 years
- Ability to walk at least 100 meters, with or without an assistive device, and without requiring rest
- Self-reported perception of impaired balance during standing or walking in daily activities
You likely can't join if
- Uncorrected visual problems
- Cognitive impairment affecting comprehension of instructions or completion of self-administered outcome measures
- Ongoing MS exacerbation or paroxysmal vertigo
- Concurrent neurological or orthopedic conditions affecting balance
- Recent participation in rehabilitation therapies (physical therapy, occupational therapy, or vestibular therapy) within one month prior to recruitment
- Planned or recent injection of botulinum toxin to the legs during the intervention period
See the full eligibility criteria
- Confirmed diagnosis of Multiple Sclerosis (MS) according to the revised McDonald criteria
- Age ≤ 65 years
- Ability to walk at least 100 meters, with or without an assistive device, and without requiring rest
- Self-reported perception of impaired balance during standing or walking in daily activities
- Uncorrected visual problems
- Cognitive impairment affecting comprehension of instructions or completion of self-administered outcome measures
- Ongoing MS exacerbation or paroxysmal vertigo
- Concurrent neurological or orthopedic conditions affecting balance
- Recent participation in rehabilitation therapies (physical therapy, occupational therapy, or vestibular therapy) within one month prior to recruitment
- Planned or recent injection of botulinum toxin to the legs during the intervention period
- Peripheral nerve damage affecting the legs
- Contraindications to electrical stimulation, including:implanted electronic device, active cancer or radiation treatment within the past 6 months, uncontrolled epilepsy, skin rash or open wound at electrode site...
The study team makes the final eligibility decision.
Where it is enrolling
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 6 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.