Anal Cancer study: Self-sampling vs Nylon-flocked Swab
Official title Self-sampling to Optimize Anal Lesion Outcomes
ClinicalTrials.gov ID: NCT07192055
What this study is testing
- What it's testing
- The study wants to find out if self‑sampling helps more people get screened and attend follow‑up appointments, and whether it changes test results. It also compares self‑sampling with provider‑taken samples to see which leads to better clinic attendance.
- Who it's for
- Adults who have an increased risk of anal cancer.
- What's involved
- Participants will either collect their own anal sample or have a health‑care provider collect it, then have the sample examined (cytology) and may be asked to attend a high‑resolution anoscopy appointment.
- Time commitment
- Involves a one‑time sample collection and any follow‑up visits needed for test results and possible further exams.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 and older. Healthy volunteers may be eligible.
You may be able to join if
- A potential study subject who meets all of the following is eligible to participate in the study.
- Age ≥ 35 years for those who are HIV-positive or ≥ 45 years for those who are HIV-negative.
- A cisgender or transgender sexual minority man, or
- A transgender woman who has sex with men.
- Resides in Chicago, Houston, or Milwaukee metropolitan area.
You likely can't join if
- Was a participant in the PAC Self-Swab Study in Milwaukee.
- Currently on anticoagulants, with the exception of aspirin or non-steroidal anti-inflammatory drugs (NSAIDs), e.g., ibuprofen, naproxen.
- Diagnosed with hemophilia, cirrhosis with bleeding varices, or thrombocytopenia.
- Presence of any contraindicating severe disease or condition, e.g., anal stenosis.
- Plans to move within 12 months after enrollment.
See the full eligibility criteria
- A potential study subject who meets all of the following is eligible to participate in the study. Note that these criteria apply regardless of HPV vaccination status or disability status.
- Age ≥ 35 years for those who are HIV-positive or ≥ 45 years for those who are HIV-negative.
- A cisgender or transgender sexual minority man, or
- A transgender woman who has sex with men.
- Resides in Chicago, Houston, or Milwaukee metropolitan area.
- Is willing to attend a study clinic.
- Speak and understand either English or Spanish
- Ability to understand a written informed consent document, and the willingness to sign it.
- Was a participant in the PAC Self-Swab Study in Milwaukee.
- Currently on anticoagulants, with the exception of aspirin or non-steroidal anti-inflammatory drugs (NSAIDs), e.g., ibuprofen, naproxen.
- Diagnosed with hemophilia, cirrhosis with bleeding varices, or thrombocytopenia.
- Presence of any contraindicating severe disease or condition, e.g., anal stenosis.
- Plans to move within 12 months after enrollment.
The study team makes the final eligibility decision.
Where it is enrolling
- Chicago, Illinois, United States
- Houston, Texas, United States
- Milwaukee, Wisconsin, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Chicago, Illinois, United States; Houston, Texas, United States; Milwaukee, Wisconsin, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.