Osteoarthritis Hand study: Corticosteroid injection vs Low-dose radiotherapy
Official title Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
ClinicalTrials.gov ID: NCT07217405
What this study is testing
What is Corticosteroid injection (CSI)?
This is an investigational injection being studied as a potential treatment for hand osteoarthritis. It is designed to reduce inflammation and pain in the joints.
Also referred to as Methylprednisolone, Lidocaine.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether low-dose radiation works as well as steroid shots. It looks at how well each option treats hand arthritis.
- Who it's for
- You may be able to join if you have arthritis in your hand or wrist.
- What's involved
- You would get either low-dose radiation or a steroid shot. You would also have check-ups to see how your pain changes.
- Time commitment
- The study lasts for a set time with visits for treatment and follow-up.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- Patient at Mayo Clinic, Rochester, MN
- Age 50 years or older
- Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
- Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
- Ability to complete study questionnaires
You likely can't join if
- History of previous surgery to the affected hand(s)
- Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
- Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
- Recent injury (within last 1 month) to the affected hand causing current pain
- History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
- Active use of opioid pain medication(s) or oral steroids within the last 3 months
See the full eligibility criteria
- Patient at Mayo Clinic, Rochester, MN
- Age 50 years or older
- Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
- Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
- Ability to complete study questionnaires
- History of previous surgery to the affected hand(s)
- Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
- Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
- Recent injury (within last 1 month) to the affected hand causing current pain
- History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
- Active use of opioid pain medication(s) or oral steroids within the last 3 months
- Fibromyalgia or central sensitization syndrome
- Hand CSI or other hand injection within the past 3 months
- History of hand LDRT within the past 3 months
- Poorly controlled diabetes (HbA1c \> 10%)
- Active infection
- Current pregnancy
The study team makes the final eligibility decision.
Where it is enrolling
- Rochester, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Rochester, Minnesota, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.