Epilepsy study: Visual Exploration vs Ambulatory Exploration
Official title Hippocampal Oscillations During Exploration
ClinicalTrials.gov ID: NCT07224191
What this study is testing
- What it's testing
- The study aims to see how looking around and moving around relate to activity in the hippocampus, a brain area important for memory.
- Who it's for
- People with epilepsy who have had brain surgery or have an implanted responsive neurostimulation (RNS) device.
- What's involved
- Participants will have their brain activity recorded with high‑resolution iEEG while doing visual tasks, and with their RNS device while walking or exploring outside the hospital.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70. Healthy volunteers may be eligible.
You may be able to join if
- Adults (18-70 years)
- Able to provide informed consent Aim 1: Surgical epilepsy patients' Implanted hippocampal depth electrodes for Stage 1 epilepsy surgery
- MMSE\>=24 Aim 2: RNS patients Implanted RNS device with at least one hippocampal depth electrode
- At least 5 months post-implantation to avoid the post-implant effect
- Have a relatively low number of seizures, defined as \<1 generalized tonic-clonic or other seizure with potential to fall or cause injury per month
You likely can't join if
- Legally blind
- Smoking tobacco, marijuana, recreational drugs or alcohol use within 1 week of cognitive testing
- Unable to give informed consent
- Pregnancy
See the full eligibility criteria
- Adults (18-70 years)
- Able to provide informed consent Aim 1: Surgical epilepsy patients' Implanted hippocampal depth electrodes for Stage 1 epilepsy surgery
- MMSE\>=24 Aim 2: RNS patients Implanted RNS device with at least one hippocampal depth electrode
- At least 5 months post-implantation to avoid the post-implant effect
- Have a relatively low number of seizures, defined as \<1 generalized tonic-clonic or other seizure with potential to fall or cause injury per month
- Able to walk and wear research equipment without assistance
- MMSE\>=24 Aim 2: Healthy Control Able to walk and wear research equipment without assistance
- Legally blind
- Smoking tobacco, marijuana, recreational drugs or alcohol use within 1 week of cognitive testing
- Unable to give informed consent
- Pregnancy
The study team makes the final eligibility decision.
Where it is enrolling
- New York, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at New York, New York, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.