Chronic Kidney Disease study: OJR520
Official title Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
ClinicalTrials.gov ID: NCT07235059
What this study is testing
What is OJR520?
OJR520 is an investigational medicine, being studied as a potential treatment for chronic kidney disease.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to find out if OJR520 is safe, how well people tolerate it, and how the drug moves through and affects the body.
- Who it's for
- Adults who are healthy or have chronic kidney disease.
- What's involved
- Participants will receive OJR520 and undergo blood draws and other checks to monitor safety and drug levels.
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Healthy male and female participants in good health as determined by past medical history, physical examination, vital signs, 12-lead ECG, and...
- Male and female participants 18 to 65 years of age.
You likely can't join if
- Women of childbearing potential.
- Clinically significant abnormal blood pressure, defined as SBP \ 140 mmHg or DBP \ 95 mmHg.
- Abnormal resting HR, defined as \ 90 bpm. Part B \& C (CKD)
- History of, or currently active, significant illness or medical disorders including, but not limited to, cancer (except for non-melanoma skin...
- Clinically significant aortic stenosis or mitral insufficiency as identified via echocardiography.
- History of myocardial infarction (MI), stroke, coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), or transient ischemic...
The study team makes the final eligibility decision.
Where it is enrolling
- Miami, Florida, United States
- Berlin, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Miami, Florida, United States; Berlin, Germany. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.