Multiple Myeloma study: CAR19-BCMA dual-target CAR-T
Official title CAR19-BCMA Dual-target CAR-T in the Treatment of Relapsed / Refractory Multiple Myeloma
ClinicalTrials.gov ID: NCT07249073
What this study is testing
What is CAR19-BCMA dual-target CAR-T?
An investigational CAR‑T cell injection being studied for relapsed or refractory multiple myeloma.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study will look at how safe the CAR19‑BCMA dual‑target CAR‑T treatment is and find the highest dose that patients can tolerate.
- Who it's for
- Adults with relapsed or refractory multiple myeloma who have tried other treatments.
- What's involved
- Participants will receive the CAR‑T cells and have regular visits for monitoring and blood tests to check safety and side effects.
- Time commitment
- The study lasts about 6 months, with several clinic visits and blood draws during and after the treatment.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- The expression of BCMA and / or CD19 in myeloma cells was positive confimed by flow cytometry or immunohistochemistry;
- Creatinine ≤ 2 × ULN;
- Left ventricular ejection fraction ≥ 50%;
- Blood oxygen saturation \>90%;
- Total bilirubin ≤ 1.5 × ULN; ALT and AST ≤ 2.5 × ULN; 8. people with pregnancy plans must agree to take contraception before enrollment in the study...
You likely can't join if
- 1\. There were severe cardiac insufficiency and left ventricular ejection fraction \<50%; 2.
The study team makes the final eligibility decision.
Where it is enrolling
- Tianjin, Tianjin Municipality, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Tianjin, Tianjin Municipality, China. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.