PTSD study: Exercise
Official title Determining the Benefits of Exercise on Cardiovascular Risk in PTSD
ClinicalTrials.gov ID: NCT07260032
What this study is testing
- What it's testing
- The study aims to find out how exercise affects brain activity and inflammation in blood vessels.
- Who it's for
- This study is looking for people who have PTSD symptoms and signs of or high risk for artery disease.
- What's involved
- Participants will undergo a special scan called PET/MRI (a detailed brain and body image) to check for changes in the brain and blood vessels.
- Time commitment
- The source text does not specify the total duration or number of visits required.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Age 18-65 years
- Trauma exposure
- PTSD symptoms
- Subclinical atherosclerotic CVD (e.g., coronary, cerebrovascular, or peripheral arterial plaque or calcifications on imaging), clinical...
- Ability to understand and sign informed consent
You likely can't join if
- History of stroke, brain surgery, or seizure
- Use of certain CVD medications (e.g., beta-blockers, high-intensity statins [e.g., rosuvastatin 20/40 mg and atorvastatin 40/80 mg], PCSK-9...
- Psychiatric or cardiovascular medication change within 4 weeks (i.e., stable regimen is allowed)
- Unstable blood pressure or cardiac arrhythmia
- Currently in a supervised or graduated exercise program
- Neurological or systemic inflammatory disease/current systemic anti-inflammatory therapy
See the full eligibility criteria
- Age 18-65 years
- Trauma exposure
- PTSD symptoms
- Subclinical atherosclerotic CVD (e.g., coronary, cerebrovascular, or peripheral arterial plaque or calcifications on imaging), clinical atherosclerotic CVD (e.g., myocardial infarction or revascularization), or...
- Ability to understand and sign informed consent
- History of stroke, brain surgery, or seizure
- Use of certain CVD medications (e.g., beta-blockers, high-intensity statins [e.g., rosuvastatin 20/40 mg and atorvastatin 40/80 mg], PCSK-9 inhibitors)
- Psychiatric or cardiovascular medication change within 4 weeks (i.e., stable regimen is allowed)
- Unstable blood pressure or cardiac arrhythmia
- Currently in a supervised or graduated exercise program
- Neurological or systemic inflammatory disease/current systemic anti-inflammatory therapy
- Moderate/severe alcohol/substance use disorder
- Current mania/psychosis
- Weight \>300 lbs.
- Claustrophobia
- Pregnancy
- Metal implants
- Uncontrolled hyperglycemia (HgbA1c\>7.5%)
- people who have had significant radiation exposure as part of research (\>2 nuclear tests, computed tomography images, or fluoroscopic procedures) during the preceding 12-months
The study team makes the final eligibility decision.
Where it is enrolling
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Boston, Massachusetts, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.