Prediabetes study: Cold water
Official title Crocus Sativus Tepals Water Extract in Obesity and Prediabetes
ClinicalTrials.gov ID: NCT07261475
What this study is testing
What is Crocus sativus tepals cold aqueous extract?
An investigational botanical extract being studied as a potential treatment for prediabetes and obesity-related metabolic issues.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see if drinking the extract before eating changes blood sugar, insulin, and energy use after a meal.
- Who it's for
- Adults who are overweight, obese, or have prediabetes.
- What's involved
- Participants will come to the clinic twice, drink the extract on one visit and water on the other (order random), then eat a standard slice of white bread while blood pressure, metabolism, and blood samples are taken before and after the meal.
- Time commitment
- Two clinic visits at least a week apart, each lasting a few hours.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 65
You may be able to join if
- Obesity type I (ITM \> 30 kg/m2) and/or
- Prediabetes (fasting glucose levels 6,1 - 6,9 mmol/L)
You likely can't join if
- Gastrointestinal diseases
- Diabetes mellitus of any type
- Pregnant or lactating, without contraception
- Serious clinical conditions such as cancer, severe infections, severe psychiatric disorders, autoimmune diseases, inflammatory diseases
- Participation in another clinical trial 3 months prior to the study
- ITM greater than 35 kg/m2
See the full eligibility criteria
- Obesity type I (ITM \> 30 kg/m2) and/or
- Prediabetes (fasting glucose levels 6,1 - 6,9 mmol/L)
- Gastrointestinal diseases
- Diabetes mellitus of any type
- Pregnant or lactating, without contraception
- Serious clinical conditions such as cancer, severe infections, severe psychiatric disorders, autoimmune diseases, inflammatory diseases
- Participation in another clinical trial 3 months prior to the study
- ITM greater than 35 kg/m2
- Celiac disease of gluten intolerance
- electronic implant
The study team makes the final eligibility decision.
Where it is enrolling
- Izola, Slovenia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Izola, Slovenia. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.