Clinical trial for Pancreatic Cancer
Official title A Study of Multiparametric Ultrasound Imaging Methods
ClinicalTrials.gov ID: NCT07270237
What this study is testing
- What it's testing
- The study compares multiparametric ultrasound (mpUS) to standard ultrasound and other tests to see if it gives clearer information about cancerous and non‑cancerous tissue.
- Who it's for
- Adults with pancreatic cancer or thyroid nodules who can undergo ultrasound imaging.
- What's involved
- Participants will receive mpUS scans and standard ultrasound scans, and may have other routine tests done for comparison.
- Time commitment
- The study involves a few ultrasound visits; the exact number and duration are not specified in the source.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- 10 years younger than the earliest pancreatic cancer diagnosis in the family
- Be at least 50 years old
- Be at least 40 years old if diagnosed with FAMMM syndrome (CDKN2A/p16) or Hereditary Pancreatitis (PRSS1, SPINK1/PST1, CTRC, CPA1 or other candidate...
- Be at least 35 years old if diagnosed with Peutz-Jeghers syndrome (STK11 aka LKB1)
- Not pregnant and not Nursing
You likely can't join if
- Unable to sign an informed consent for medical or other reasons; residents outside the continental United States
- Under 18 years of age Cohort 3 -Thyroid nodule assessment with multiparametric ultrasound (mpUS) imaging
- Unable to sign an informed consent for medical or other reasons; residents outside the continental United States
- Under 18 years of age
See the full eligibility criteria
- 10 years younger than the earliest pancreatic cancer diagnosis in the family
- Be at least 50 years old
- Be at least 40 years old if diagnosed with FAMMM syndrome (CDKN2A/p16) or Hereditary Pancreatitis (PRSS1, SPINK1/PST1, CTRC, CPA1 or other candidate hereditary pancreatitis genes)
- Be at least 35 years old if diagnosed with Peutz-Jeghers syndrome (STK11 aka LKB1)
- Not pregnant and not Nursing
- Relatives at least 21 years old with other high-risk clinical criteria that warrants pancreatic cancer surveillance or follow-up as determined by the project leader (Dr. Vineet Rolston)
- Must agree to be contacted for follow-up
- Have at least two affected relatives who are a first-degree relative to each other, of whom at least one is a first degree relative to the individual OR have at least two affected first-degree relatives on the same side...
- APC (Familial Adenomatous Polyposis (FAP) and Attenuated FAP syndrome
- BRCA1(Hereditary Breast and Ovarian Cancer Symptoms)
- MLH1, MSH2, MSH6, PMS2, or EPCAM (Lynch Syndrome)
- PALB2
- TP53 (Li-Fraumeni Syndrome)
- Other established pancreatic cancer predisposition gene per project leader's discretion
- CDKN2A/p16 (Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM))
- STK11 aka LKB1 (Peutz-Jeghers Syndrome)
- PRSS1, SPINK1/PST1, CTRC, CPA1 or other candidate hereditary pancreatitis genes per project leader's discretion
- ATM (ataxia telangiectasia mutated)
- BRCA 2(Hereditary Breast and Ovarian Cancer Symptoms)
- Patients with pancreatic ductal adenocarcinoma
- Are undergoing endoscopic ultrasound-guided tissue core biopsy as part of their standard of care
- Not pregnant and not nursing Cohort 3 - Thyroid nodule assessment with multiparametric ultrasound (mpUS) imaging: Patient Group: those with a thyroid nodule that will be biopsied whether they have known cancer or not
- Are undergoing ultrasound-guided thyroid biopsy as part of their standard of care
- No known cancer diagnosis or thyroid nodules
- Age ≥ 18
- Able to understand and give informed consent
- Not pregnant and not nursing
- Unable to sign an informed consent for medical or other reasons; residents outside the continental United States
- Under 18 years of age Cohort 3 -Thyroid nodule assessment with multiparametric ultrasound (mpUS) imaging
- Unable to sign an informed consent for medical or other reasons; residents outside the continental United States
- Under 18 years of age
The study team makes the final eligibility decision.
Where it is enrolling
- Basking Ridge, New Jersey, United States
- Middletown, New Jersey, United States
- Montvale, New Jersey, United States
- Commack, New York, United States
- Harrison, New York, United States
- New York, New York, United States
- Uniondale, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Basking Ridge, New Jersey, United States; Middletown, New Jersey, United States; Montvale, New Jersey, United States; Commack, New York, United States; Harrison, New York, United States; New York, New York, United States and 1 more location. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.