Clinical trial for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Official title Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis
ClinicalTrials.gov ID: NCT07270601
What this study is testing
- What it's testing
- The study wants to see if an ultrasound can accurately tell how much fat is in the liver. It aims to find a cheaper, non‑invasive way to monitor liver health.
- Who it's for
- Adults who have metabolic dysfunction‑associated steatotic liver disease or non‑alcoholic fatty liver disease, especially if they have obesity, diabetes, high blood pressure, or high cholesterol.
- What's involved
- Participants will have one or more ultrasound examinations of the liver and may answer simple health questions. No surgery or needles are involved.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Adult patients (age 18 - 75 years)
- Consent to participate in the study
- Diagnosed or suspected MASLD from the hepatology clinic, OR
- Adult patients (age 18 - 75 years)
- Consent to participate in the study
You likely can't join if
- Pregnancy or nursing.
- Contraindications to MRI including, but not limited to, severe claustrophobia, pacemaker, or existing metallic/mechanical implant(s).
- Acute illness/cognitive impairment resulting in an inability to cooperate with the MRI and ultrasound breath-holding instructions.
- BMI \> 35 kg/m2
- History of excessive alcohol consumption according to the updated MASLD criteria (\>2 drinks/day OR \>210 grams/week for males AND \>1 drink/day OR...
- Known acute or chronic hepatitis; or other etiology of liver disease.
See the full eligibility criteria
- Adult patients (age 18 - 75 years)
- Consent to participate in the study
- Diagnosed or suspected MASLD from the hepatology clinic, OR
- Adult patients (age 18 - 75 years)
- Consent to participate in the study
- No suspicion of MASLD by laboratory/imaging/clinical examinations
- Absence of known pre-existing conditions (metabolic syndrome, diabetes mellitus, obesity, insulin resistance, dyslipidemia, etc.)
- Pregnancy or nursing.
- Contraindications to MRI including, but not limited to, severe claustrophobia, pacemaker, or existing metallic/mechanical implant(s).
- Acute illness/cognitive impairment resulting in an inability to cooperate with the MRI and ultrasound breath-holding instructions.
- BMI \> 35 kg/m2
- History of excessive alcohol consumption according to the updated MASLD criteria (\>2 drinks/day OR \>210 grams/week for males AND \>1 drink/day OR \>140 grams/week for females) or drug use over the past 2 years.
- Known acute or chronic hepatitis; or other etiology of liver disease.
- Presence of known congenital hepatic anomaly.
- Known cirrhosis
- Known active cancer
The study team makes the final eligibility decision.
Where it is enrolling
- Seattle, Washington, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Seattle, Washington, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.