Clinical trial for Aphasia, Acquired
Official title Aphasia Physical EXercise Study: Randomized Trial
ClinicalTrials.gov ID: NCT07281313
What this study is testing
- What it's testing
- The study wants to see if a high‑intensity workout can improve physical health, language, thinking, movement, and mood in people with post‑stroke aphasia.
- Who it's for
- Adults who have aphasia caused by a recent stroke.
- What's involved
- Participants are randomly assigned to a high‑intensity interval training workout or a low‑intensity routine, done in a group setting for 12 weeks, with tests before, after, and 12 weeks later.
- Time commitment
- A 12‑week exercise program with group sessions and three assessment visits (start, end, and 12‑week follow‑up).
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Aphasia following ischemic or hemorrhagic stroke
- Aphasia as determined by a standardized language test (Western Aphasia Battery Aphasia Quotient \< 93.8 at study intake)
- At least 6 months from the last stroke
- Proficient in English before the stroke
- At least 8 years of education
You likely can't join if
- Prior history of dementia, neurologic illness (other than stroke), or recent (last 3 years) substance abuse
- Significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing
- Self-report uncontrolled cardiorespiratory and/or metabolic disorders incompatible with exercise
See the full eligibility criteria
- Aphasia following ischemic or hemorrhagic stroke
- Aphasia as determined by a standardized language test (Western Aphasia Battery Aphasia Quotient \< 93.8 at study intake)
- At least 6 months from the last stroke
- Proficient in English before the stroke
- At least 8 years of education
- Between the ages of 18 and 80
- Independent with ambulation without a device (single-point cane accepted)
- Medically stable with no contraindications to participate in regular physical exercise as determined by the patients' own primary care provider or other treating provider.
- Prior history of dementia, neurologic illness (other than stroke), or recent (last 3 years) substance abuse
- Significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing
- Self-report uncontrolled cardiorespiratory and/or metabolic disorders incompatible with exercise
The study team makes the final eligibility decision.
Where it is enrolling
- Berkeley, California, United States
- Hayward, California, United States
- San Francisco, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Berkeley, California, United States; Hayward, California, United States; San Francisco, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.