Clinical trial for Nicotine Addiction
Official title Non-Invasive Deep Brain Neuromodulation for Smoking Cessation
ClinicalTrials.gov ID: NCT07298902
What this study is testing
- What it's testing
- This study is testing whether low‑intensity focused ultrasound can help people stop smoking. It looks at how the sound waves affect the brain areas linked to nicotine addiction.
- Who it's for
- You may be able to join if you smoke cigarettes and have tried many ways to quit but still struggle.
- What's involved
- You will receive ultrasound treatments that send gentle sound waves to your brain. You will also have brain scans and check‑ins to see how you feel and if the treatment works.
- Time commitment
- The study lasts several weeks, with multiple treatment sessions and follow‑up visits to monitor progress.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Must be a smoker for 5 or more years and within 20 to 60 years of age
- Must not meet
You likely can't join if
- for MRI scanning (e.g., non-fixed magnetizable objects)
- Must not have ongoing unstable medical, neurological or psychiatric illness as determined by a combination of history, medical record, and/or...
- Must be a current smoker with average of 5 cigarettes or more a day for the last month or longer.
- Failed TMS screening questionnaire.
- Significant alcohol or other drug use (substance dependence within the recent months) or positive urine toxicology screen for substance not...
- Cannot refrain from using alcohol and/or marijuana 24 hours or more prior to experiments.
See the full eligibility criteria
- Must be a smoker for 5 or more years and within 20 to 60 years of age
- Must not meet
- for MRI scanning (e.g., non-fixed magnetizable objects)
- Must not have ongoing unstable medical, neurological or psychiatric illness as determined by a combination of history, medical record, and/or examination.
- Must be a current smoker with average of 5 cigarettes or more a day for the last month or longer.
- Failed TMS screening questionnaire.
- Significant alcohol or other drug use (substance dependence within the recent months) or positive urine toxicology screen for substance not prescribed other than nicotine or marijuana dependence.
- Cannot refrain from using alcohol and/or marijuana 24 hours or more prior to experiments.
- Taking \> 400 mg clozapine/day and not on anti-seizure medication(s) with sufficient dose.
- Woman who is pregnant (child-bearing potential but not on contraceptive and missing menstrual period; or by self-report
- In ongoing smoking cessation treatment, clinical trial, or nicotine replacements (except for the current study)
The study team makes the final eligibility decision.
Where it is enrolling
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Houston, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.