Coeliac Disease study: Symprove Probiotic
Official title Efficacy of Symprove Probiotics in Coeliac Disease
ClinicalTrials.gov ID: NCT07360106
What this study is testing
- What it's testing
- The study aims to find out if a probiotic drink can ease ongoing gut symptoms and restore healthy gut bacteria in people with coeliac disease.
- Who it's for
- People with coeliac disease who follow a strict gluten-free diet but still experience gut symptoms like bloating or pain.
- What's involved
- Participants will drink a probiotic supplement daily and provide stool samples to check gut bacteria while tracking their symptoms and quality of life.
- Time commitment
- The study involves regular monitoring over time, though the specific duration is not stated in the provided text.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Adults aged 18-65 years with biopsy-confirmed coeliac disease (CD)
- Normal duodenal biopsy (Marsh 0 or Marsh I) within the last 12 months, confirming histological remission
- Adherence to a strict gluten-free diet (GFD) for at least 6 months
- Persistent gastrointestinal (GI) symptoms for at least 6 months despite adherence to GFD and histological remission
- Ability to provide written informed consent
You likely can't join if
- Active gluten ingestion or non-adherence to a gluten-free diet
- Use of antibiotics within the past 3 months
- Use of probiotics within the past 3 months
- Known comorbidities affecting gastrointestinal function (e.g., Crohn's disease, ulcerative colitis, irritable bowel syndrome with severe diarrhea, or...
- Pregnancy or lactation
- Inability to provide informed consent
The study team makes the final eligibility decision.
Where it is enrolling
- Sheffield, South Yorkshire, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Sheffield, South Yorkshire, United Kingdom. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.