Clinical trial for Migraine
Official title Dietary Intervention for Migraine Relief
ClinicalTrials.gov ID: NCT07360405
What this study is testing
- What it's testing
- This study is testing whether a low-glutamate diet reduces migraine days and pain. It also looks at how this diet affects body markers linked to migraines.
- Who it's for
- You may be able to join if you are an adult who gets migraines.
- What's involved
- You would follow a low-glutamate diet or keep your usual diet. You would track headaches, fill out forms, and give blood samples.
- Time commitment
- The study includes a start period, the diet phase, and later check-ins.
You might receive a placebo (an inactive treatment) instead of the study drug. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Men and women of all races and ethnicities
- Age 18-75 years
- 8 headache days per month, and
- 4 migraine days per month
- Migraine onset before age 50
You likely can't join if
- Current pregnancy, plans to become pregnant during the study timeframe, or current breastfeeding
- Current use of medications affecting glutamatergic or gamma-Aminobutyric Acid (GABA) neurotransmission (unless discontinued under physician guidance)
- Current use of quarterly injectable migraine preventive medications
- Unwillingness to modify dietary intake or to stop alcohol and marijuana use during the study
- Substance use disorder within the past year
- Diagnosed seizure disorder
See the full eligibility criteria
- Men and women of all races and ethnicities
- Age 18-75 years
- 8 headache days per month, and
- 4 migraine days per month
- Migraine onset before age 50
- On a stable medication regimen for at least 1 month prior to enrollment
- Willing to maintain stable medications throughout the study
- Willing to discontinue supplements during the study period
- Women of childbearing potential must be willing to use birth control during the study timeframe
- Current pregnancy, plans to become pregnant during the study timeframe, or current breastfeeding
- Current use of medications affecting glutamatergic or gamma-Aminobutyric Acid (GABA) neurotransmission (unless discontinued under physician guidance)
- Current use of quarterly injectable migraine preventive medications
- Unwillingness to modify dietary intake or to stop alcohol and marijuana use during the study
- Substance use disorder within the past year
- Diagnosed seizure disorder
- Severe asthma requiring past hospitalization
The study team makes the final eligibility decision.
Where it is enrolling
- Washington D.C., District of Columbia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Washington D.C., District of Columbia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.