Subclinical Hypothyroidism study: Levothyroxine
Official title Thyroid Hormone Replacement After Coronary Artery Bypass Grafting for Patients With Subclinical Hypothyroidism
ClinicalTrials.gov ID: NCT07380854
What this study is testing
What is levothyroxine?
This is an investigational thyroid hormone medicine being studied to see if it helps patients with subclinical hypothyroidism who are having heart bypass surgery. It is designed to replace the thyroid hormone that your body is not making enough of.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see whether taking levothyroxine can reduce serious heart problems, such as heart attack, stroke, or new heart rhythm issues, after bypass surgery.
- Who it's for
- It is looking for adults who have subclinical hypothyroidism and are scheduled for coronary artery bypass grafting.
- What's involved
- Participants will be randomly assigned to receive levothyroxine or not. Those in the treatment group will start the medication one day before surgery and will have regular follow‑up visits to monitor thyroid levels and heart events.
- Time commitment
- The study lasts up to five years after surgery, with follow‑up visits scheduled during that time.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 90
You may be able to join if
- Eligibility Criteria
- Adults aged 19 to 90 years.
- Patients scheduled to undergo coronary artery bypass graft (CABG) surgery.
- Subclinical hypothyroidism (SCH), defined as a normal free thyroxine (free T4) level and a thyroid-stimulating hormone (TSH) level greater than 4...
You likely can't join if
- Patients who underwent repeat or emergency CABG surgery
- Use of LT4 within the previous 4 weeks
- Use of antithyroid drug use (propylthiouracil, methimazole, or carbimazole) within the previous 3 months
- Severe comorbid conditions with a life expectancy of less than 1 year (e.g. advanced malignancy)
The study team makes the final eligibility decision.
Where it is enrolling
- Seongnam-si, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Seongnam-si, South Korea. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.