Clinical trial for Degenerative Disc Disease
Official title Biologic Injection For Adults With Lumbar Disc Herniation
ClinicalTrials.gov ID: NCT07386548
What this study is testing
- What it's testing
- The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation. The main questions it aims to answer are: Does the BMAC injection lead to better disc tissue health after surgery (as seen on MRI scans)?
- Time commitment: about 2 years
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male or female patients ≥ 18 years of age
- Clinically and/or radiographically (MRI) confirmed diagnosis of degenerative disc disease of the lumbar spine, lumbar disc herniation, and indication...
- Unresponsive to conservative/non-operative treatment for \>3 months
- Psychosocial, mental and physical ability to understand and to adhere to this protocol, especially adhering to the visit schedule follow-ups and...
You likely can't join if
- Prisoners
- Individuals who are not yet adults (infants, children, teenagers)
- Individuals who are not able to clearly understand English
- Adults with diminished capacity to consent
- Major cognitive impairment causing to inability to understand and provide informed consent
- Active malignancy
See the full eligibility criteria
- Male or female patients ≥ 18 years of age
- Clinically and/or radiographically (MRI) confirmed diagnosis of degenerative disc disease of the lumbar spine, lumbar disc herniation, and indication for lumbar microdiscectomy surgery
- Unresponsive to conservative/non-operative treatment for \>3 months
- Psychosocial, mental and physical ability to understand and to adhere to this protocol, especially adhering to the visit schedule follow-ups and observe the treatment plan
- Prisoners
- Individuals who are not yet adults (infants, children, teenagers)
- Individuals who are not able to clearly understand English
- Adults with diminished capacity to consent
- Major cognitive impairment causing to inability to understand and provide informed consent
- Active malignancy
- Active chronic or acute infection
- Autoimmune disorder that impacts the lumbar spine (ankylosing spondylitis, lupus e.g.)
- Bone marrow-derived or non-bone marrow-derived cancer
- Low platelet count or clotting disorders
- Prior surgery at the level to be treated or the adjacent level
The study team makes the final eligibility decision.
Where it's taking place
- Manhattan, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 2 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Manhattan, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.