Levothyroxine study: L-thyroxine
Official title Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism
ClinicalTrials.gov ID: NCT07393165
What this study is testing
What is L‑thyroxine?
An investigational oral medication being studied for children with subclinical hypothyroidism to improve cardiac function. is designed to replace or supplement thyroid hormone in the body.
Also referred to as Levothyroxine.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to find out whether giving levothyroxine improves heart function in children who have subclinical hypothyroidism.
- Who it's for
- Children who have been diagnosed with subclinical hypothyroidism.
- What's involved
- Participants will receive levothyroxine treatment and have their heart function checked through tests and visits.
- Time commitment
- The study will last for the duration of the treatment period, with regular visits for medication and heart function monitoring.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 4 to 15
You may be able to join if
- Age from 4 to 15 years.
- Both sexes.
- Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU/L with normal free T4 and ft3 in different measurement 4 - 6 weeks apart.
You likely can't join if
- Overweight and obesity
- Hypertension
- Previous use of levothyroxine, antiepileptic drugs, or cardiac drugs within the last 6 months.
- Arrhythmia.
- Congenital or acquired heart disease
- Liver or kidney disease
See the full eligibility criteria
- Age from 4 to 15 years.
- Both sexes.
- Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU/L with normal free T4 and ft3 in different measurement 4 - 6 weeks apart.
- Overweight and obesity
- Hypertension
- Previous use of levothyroxine, antiepileptic drugs, or cardiac drugs within the last 6 months.
- Arrhythmia.
- Congenital or acquired heart disease
- Liver or kidney disease
- Hyperlipidemia
- Diabetes
- Infectious diseases
- Respiratory diseases
- Malignancies
The study team makes the final eligibility decision.
Where it is enrolling
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 4 years to 15 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.