Recruiting PHASE1, PHASE2 Arthritis, Rheumatoid

Clinical trial for Arthritis, Rheumatoid

Official title A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

ClinicalTrials.gov ID: NCT07412704

What this study is testing

What is BMS-986528?

BMS-986528 is an investigational medicine, being studied as a potential treatment for arthritis, rheumatoid.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the preliminary evidence of disease-modifying effect of BMS-986528 in participants with refractory, difficult-to-treat rheumatoid arthritis (RA).
  • Phase 2: a mid-size study of how well it works

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 65

You may be able to join if

  • \- Adult participants with rheumatoid arthritis (RA) who meet definition of difficult-to-treat.

You likely can't join if

  • Juvenile arthritis or onset of inflammatory arthritis before age 18.
  • Seronegative RA participants in whom polymyalgia rheumatica has not been ruled out.
  • Active fibromyalgia with pain symptoms or signs that would interfere with joint assessment.
  • Other protocol-defined Inclusion/Exclusion criteria apply.

The study team makes the final eligibility decision.

Where it's taking place

  • La Jolla, California, United States
  • Loma Linda, California, United States
  • Palo Alto, California, United States
  • Aurora, Colorado, United States
  • Denver, Colorado, United States
  • South Miami, Florida, United States
  • New York, New York, United States
  • Portland, Oregon, United States
  • Philadelphia, Pennsylvania, United States
  • DeSoto, Texas, United States
  • Merksem, Flanders, Belgium
  • Leuven, Belgium
  • Aparecida de Goiânia, Goiás, Brazil
  • Porto Alegre, Rio Grande do Sul, Brazil
  • Valinhos, São Paulo, Brazil
  • Beijing, Beijing Municipality, China
  • Guangzhou, Guangdong, China
  • Zhengzhou, Henan, China
  • Nanchang, Jiangxi, China
  • Shanghai, Shanghai Municipality, China

+ 17 more site(s).

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include La Jolla, California, United States; Loma Linda, California, United States; Palo Alto, California, United States; Aurora, Colorado, United States; Denver, Colorado, United States; South Miami, Florida, United States and 31 more location(s). Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.