Clinical trial for Amyotrophic Lateral Slerosis
Official title Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis
ClinicalTrials.gov ID: NCT07413718
What this study is testing
- What it's testing
- Amyotrophic Lateral Sclerosis (ALS) progressively damages the nerve cells responsible for voluntary muscle movement. Over time, this leads to weakness in different muscles such as those used for movement or breathing.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Patients diagnosed with spinal ALS
- men and women
- diagnosis date less than two years ago, according to the "El Escorial" criteria (Appendix 2)
- PIM above the lower limit of normal
- Preserved lung function (FVC ≥ 80%, FEV1 ≥ 80%, FEV1/FVC ≥ 80%) and normal values in supine position
You likely can't join if
- Patients with signs of respiratory muscle weakness (MIP and MEP below the LLN and abnormal decubitus tests19-21)
- Nocturnal hypoventilation
- Inability to perform the measurement tests
- Inability to understand and perform the exercises
- Any contraindication to the use of IMT. Severe psychiatric illness.
The study team makes the final eligibility decision.
Where it's taking place
- Donostia / San Sebastian, Gipuzka, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Donostia / San Sebastian, Gipuzka, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.