Diabetes Mellitus, Type 2 study: NNC0662-0419 vs Semaglutide
Official title A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
ClinicalTrials.gov ID: NCT07415954
What this study is testing
What is NNC0662-0419?
An investigational once‑daily injectable medicine being studied for type 2 diabetes.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether NNC0662-0419 can safely lower blood sugar compared to a pretend treatment or an approved medicine.
- Who it's for
- You may be able to join if you have type 2 diabetes and are not taking NNC0662-0419 yet.
- What's involved
- You will receive either NNC0662-0419, a pretend treatment, or semaglutide. The amount you get is chosen by chance. You will have visits and tests to check your blood sugar and safety.
- Time commitment
- The study lasts several weeks with multiple visits to monitor your health and blood sugar levels.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Male or female (sex at birth).
- Age 18-75 years (both inclusive) at the time of signing the informed consent.
- Glycated haemoglobin (HbA1c) of 7.0-10.0 percent (%) (53-86 millimoles per mole [mmol/mol]) (both inclusive) as assessed by central laboratory at...
- Willingness to obtain a high weight loss (greater than [\>] 25% of weight at baseline).
You likely can't join if
- Treatment with any medication for the indication of diabetes or obesity other than stated in the inclusion criteria within 90 days before screening.
- Uncontrolled and potentially unstable diabetic retinopathy or maculopathy.
- Known hypoglycaemic unawareness as indicated by the investigator according to Clarke's Questionnaire.
The study team makes the final eligibility decision.
Where it is enrolling
- Lancaster, California, United States
- Lomita, California, United States
- Long Beach, California, United States
- Los Alamitos, California, United States
- San Diego, California, United States
- Walnut Creek, California, United States
- Hollywood, Florida, United States
- Miami, Florida, United States
- Miramar, Florida, United States
- Weston, Florida, United States
- Blackfoot, Idaho, United States
- Chicago, Illinois, United States
- Springfield, Missouri, United States
- Greensboro, North Carolina, United States
- Statesville, North Carolina, United States
- Dayton, Ohio, United States
- Memphis, Tennessee, United States
- Dallas, Texas, United States
- Houston, Texas, United States
- Shavano Park, Texas, United States
+ 27 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Lancaster, California, United States; Lomita, California, United States; Long Beach, California, United States; Los Alamitos, California, United States; San Diego, California, United States; Walnut Creek, California, United States and 41 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.