Clinical trial for Periarticular Block
Official title Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA
ClinicalTrials.gov ID: NCT07430085
What this study is testing
What is bupivacaine-meloxicam (extended release)?
bupivacaine-meloxicam (extended release) is an investigational medicine, being studied as a potential treatment for periarticular block.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether Zynrelef helps with pain after knee surgery. It also looks at how much pain medicine people need.
- Who it's for
- You may be able to join if you are having robot-assisted total knee replacement surgery.
- What's involved
- You would get a pain shot around your knee after surgery. You would rate your pain and track your pain medicine use.
- Time commitment
- The study follows you for 72 hours after your surgery.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 89
You may be able to join if
- Males or females aged 18-89 years
- Diagnosed with knee osteoarthritis requiring surgical intervention
- Indicated for unilateral RATKA
You likely can't join if
- Pediatric, pregnant, or incarcerated patients
- BMI of more than 45 kg/m2
- Prolonged opioid use history of \>5 mg/day for \>1 month
- History of contralateral TKA \<2 years prior to the index TKA
- Type 1 Hypersensitivity to NSAIDs or local anesthetics
- Diagnosis of severe renal disease
The study team makes the final eligibility decision.
Where it is enrolling
- Cranberry Township, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 89 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Cranberry Township, Pennsylvania, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.