Clinical trial for Knee Osteoarthritis (Knee OA)
Official title Advanced Brain Imaging-TKA (fMRI-TKA)
ClinicalTrials.gov ID: NCT07464080
What this study is testing
- What it's testing
- The study wants to find out if patterns in brain scans before and after knee replacement can tell doctors which patients will be satisfied with the surgery and which may still have pain or trouble with daily activities.
- Who it's for
- Adults who are scheduled to have total knee replacement surgery for knee osteoarthritis or chronic knee pain.
- What's involved
- Participants will have brain MRI scans before and after surgery, fill out questionnaires about pain and function, and have their knee function evaluated by a clinician.
- Time commitment
- The study lasts from before surgery through a follow‑up period after surgery, with MRI scans and assessments at those times.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male and female patients aged 18 years or older
- Primary TKA
- Diagnosis of osteoarthritis, inflammatory arthritis, or osteonecrosis
You likely can't join if
- Inability or refusal to sign informed consent form
- Non-English or French speaking, and no licensed translator, family member or substitute decision maker available
- History of major neurological disorders (e.g traumatic brain injury, epilepsy, multiple sclerosis
- Cognitive impairment or dementia
- Revision and/or Bilateral TKA
- Chronic Opioid use
The study team makes the final eligibility decision.
Where it is enrolling
- Ottawa, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Ottawa, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.