Atopic Dermatitis study: Sodium chloride tablets
Official title The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease
ClinicalTrials.gov ID: NCT07487831
What this study is testing
What is Sodium chloride tablets?
Investigational sodium chloride tablets being studied as a potential treatment for atopic dermatitis (eczema).
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Researchers want to see if skin sodium levels are linked to eczema or psoriasis severity and if changing salt intake changes those levels and symptoms.
- Who it's for
- Adults with eczema or psoriasis who can follow a low‑salt diet and take daily tablets.
- What's involved
- Participants follow a low‑salt diet for 13 weeks, take sodium tablets for 5 weeks and a placebo for 5 weeks (or the reverse) with a 2‑week break in between, and visit the clinic up to four times for questionnaires, blood samples, diet records and a special MRI scan.
- Time commitment
- The study lasts 13 weeks and requires up to four clinic visits during that time.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Participants ages 18 years
- Willing and able to undergo non-contrast MRI.
You likely can't join if
- Contraindications to MRI (such as cardiac pacemakers, claustrophobia, non-compatible intracranial vascular clips, IUDs, or other implants)
- A cardiac event in the past 6 months
- Impaired function of the liver or kidney (glomerular filtration rate \<60 mL/min)
- Medications that influence sodium excretion (e.g., diuretics or SGLT2 inhibitors)
- Antibiotic or immunomodulatory medications within the last month
- Contraindications to sodium tablets (Topical medications used exclusively on the head/neck or hands/feet (e.g., antifungal nail treatment...
The study team makes the final eligibility decision.
Where it is enrolling
- San Francisco, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Francisco, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.