Prevention trial for Breast Cancer Risk
Official title Population Based Germline Testing for Early Detection and Prevention of Cancer
ClinicalTrials.gov ID: NCT07498829
What this study is testing
What is Genetic testing for Cancer Susceptibility Genes (CSGs)?
This is an investigational genetic test being studied to identify inherited gene changes that may increase the risk of breast, ovarian, bowel, and womb cancers. It is designed to analyze DNA samples to detect specific mutations in genes like BRCA1 and BRCA2 that are known to affect how cells repair damage.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see if offering genetic tests through an app helps more people find out if they have a gene change that raises their risk of breast, ovary, bowel, or womb cancer.
- Who it's for
- The study is looking for women, trans men, or non-binary people over 18 who have female reproductive organs and have never had this specific genetic test.
- What's involved
- Participants will use a study app to decide if they want a test. If they do, they will receive a saliva kit in the mail to send back. Some may also join an optional interview.
- Time commitment
- The study involves using the app, sending a saliva sample, and completing questionnaires, with no set end date mentioned in the text.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only. Healthy volunteers may be eligible.
You may be able to join if
- Women, trans men, and non-binary people with female reproductive organs
- ≥18 years at consent
You likely can't join if
- Individuals who have previously undergone genetic testing for one or more of the following CSGs: BRCA1, BRCA2, PALB2, RAD51C, RAD51D, BRIP1, MLH1...
- One or more first- or second-degree relative with a PV in any of above CSGs
- Inability to provide informed consent
The study team makes the final eligibility decision.
Where it is enrolling
- London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at London, United Kingdom. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.