Clinical trial for HIV
Official title Combatting HIV Or Other STIs Early (CHOOSE)
ClinicalTrials.gov ID: NCT07510048
What this study is testing
- What it's testing
- This study wants to see if a mobile health tool called PrEP Choice helps young people start taking HIV prevention medicine and keep taking it. It also checks if this method is cost-effective and looks at how well young people accept a new prevention strategy called DoxyPEP.
- Who it's for
- Young people in the United States who are interested in preventing HIV or other sexually transmitted infections.
- What's involved
- Participants will use the PrEP Choice mobile health package to help them start and stay on HIV prevention medicine. The study will also look at their use of DoxyPEP, which involves taking a specific antibiotic after sex to prevent infections.
- Time commitment
- The source text does not specify the total duration of the study or the number of required visits.
- Time commitment: about 18 months
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 13 to 24, men only. Healthy volunteers may be eligible.
You may be able to join if
- Age 13-24 years, inclusive;
- Self-reports being at increased likelihood for HIV acquisition, defined as having anal sex with a male in their lifetime;
- Owns an iOS or Android Smartphone and able to access all elements of the PrEP Choice package;
- Not currently on PrEP and interested in learning more about PrEP;
- Is not living with HIV;
You likely can't join if
- Female;
- In a mutually monogamous sexual relationship with a partner not living with HIV for the past 12 months;
- Currently participating in an treatment trial of PrEP agents, or prior enrollment in HPTN 083, HPTN 083-01, or any other study of long-acting PrEP...
- Plan to move within 18 months to an area inaccessible to a participating ATN SC;
- An employee of the participating SC; or
- Any concurrent participation in other clinical trials or behavioral intervention studies without prior approval from the protocol team.
See the full eligibility criteria
- Age 13-24 years, inclusive;
- Self-reports being at increased likelihood for HIV acquisition, defined as having anal sex with a male in their lifetime;
- Owns an iOS or Android Smartphone and able to access all elements of the PrEP Choice package;
- Not currently on PrEP and interested in learning more about PrEP;
- Is not living with HIV;
- Weighs at least 35 kg;
- Willing to receive PrEP care from a provider at a participating ATN SC;
- Able to understand, read, and speak English;
- Able to participate at the study site; and
- Willing and able to provide written informed consent.
- If of legal age or otherwise able to provide independent informed consent as determined by local law and consistent with IRB policies: Willing and able to provide written informed consent for study participation.
- If not of legal age or otherwise not able to provide independent informed consent as determined by local law and consistent with IRB policies: Parent or legal guardian is willing and able to provide written informed...
- Female;
- In a mutually monogamous sexual relationship with a partner not living with HIV for the past 12 months;
- Currently participating in an treatment trial of PrEP agents, or prior enrollment in HPTN 083, HPTN 083-01, or any other study of long-acting PrEP (including PURPOSE- 2 lenacapavir study);
- Plan to move within 18 months to an area inaccessible to a participating ATN SC;
- An employee of the participating SC; or
- Any concurrent participation in other clinical trials or behavioral intervention studies without prior approval from the protocol team.
- Any other medical, behavioral, or other conditions that in the opinion of the SC Project Lead could interfere with adherence to study procedures or the individual's ability to remain in the study for an 18-month period...
The study team makes the final eligibility decision.
Where it is enrolling
- San Francisco, California, United States
- Washington D.C., District of Columbia, United States
- Tampa, Florida, United States
- Chicago, Illinois, United States
- New Orleans, Louisiana, United States
- Memphis, Tennessee, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 18 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling male, 13 years to 24 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Francisco, California, United States; Washington D.C., District of Columbia, United States; Tampa, Florida, United States; Chicago, Illinois, United States; New Orleans, Louisiana, United States; Memphis, Tennessee, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.