Dry Eye study: Lacrifill
Official title Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses
ClinicalTrials.gov ID: NCT07510620
What this study is testing
What is Lacrifill?
An investigational eye drop being studied for dry eye in contact lens wearers.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study will see if using Lacrifill for 2–3 months is safe, easy to use, and may reduce dry‑eye symptoms and help people wear contacts longer.
- Who it's for
- Adults who wear contact lenses but find them uncomfortable for long periods because of dry eye.
- What's involved
- Participants will use Lacrifill as directed and attend study visits for eye exams and symptom questionnaires.
- Time commitment
- The study lasts about 2–3 months and includes several clinic visits to monitor safety and eye health.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 22 and older
You may be able to join if
- \>21 years of age
- Contact lens wearer
- Previous Dry Eye Treatment
- Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
- Schrimers Anesthetized less than or equal to 10
You likely can't join if
- Known allergy to Hyaluronic Acid
- Current topical ophthalmic drops other than dry eye treatment
- Uncontrolled Diabetes
- Diabetic Retinopathy
- Pregnancy or Lactating
- Corneal Surgery (except Refractive)
See the full eligibility criteria
- \>21 years of age
- Contact lens wearer
- Previous Dry Eye Treatment
- Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
- Schrimers Anesthetized less than or equal to 10
- CLDEQ-8 greater than or equal to 12
- Corneal Staining NEI grading scale greater than or equal to 1
- Known allergy to Hyaluronic Acid
- Current topical ophthalmic drops other than dry eye treatment
- Uncontrolled Diabetes
- Diabetic Retinopathy
- Pregnancy or Lactating
- Corneal Surgery (except Refractive)
- Corneal Scars
- Keratoconus
- Ocular Herpetic Keratitis
The study team makes the final eligibility decision.
Where it is enrolling
- Kingston, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 22 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Kingston, Pennsylvania, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.