Clinical trial for Rheumatoid Arthritis (RA)
Official title Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis
ClinicalTrials.gov ID: NCT07524244
What this study is testing
- What it's testing
- The study wants to see if these diets improve quality of life, reduce symptoms, and change disease activity markers in people with RA, Crohn’s disease, or ulcerative colitis.
- Who it's for
- Adults who have rheumatoid arthritis, Crohn’s disease, or ulcerative colitis.
- What's involved
- Participants are assigned to a ketogenic diet, a carnivore diet, or a wait‑list control. Those on a diet get guidance and answer questions about symptoms and quality of life at set times over 24 weeks, and they have lab tests to check nutrition, heart health, and inflammation. Wait‑list participants answer the same questions and have the same tests, then after 12 weeks they are moved to a diet group for another 12 weeks.
- Time commitment
- The study lasts 24 weeks, with visits and tests at regular intervals, and wait‑list participants switch to a diet after 12 weeks.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 64
You may be able to join if
- Diagnosed with medically verifiable IBD or medically verifiable RA
- Current personal residence in the continental U.S.
- Willingness and ability to follow dietary protocols
You likely can't join if
- Inability to provide consent
- Individuals with Type 1 or Type II Diabetes on prescription medications including insulin
- Outside of the age or BMI criteria
- No medically definitive or verifiable diagnosis of IBD or RA
- History of strictures or fistula (IBD)
- History of blood transfusion in the previous 6 months
See the full eligibility criteria
- Diagnosed with medically verifiable IBD or medically verifiable RA
- Current personal residence in the continental U.S.
- Willingness and ability to follow dietary protocols
- Inability to provide consent
- Individuals with Type 1 or Type II Diabetes on prescription medications including insulin
- Outside of the age or BMI criteria
- No medically definitive or verifiable diagnosis of IBD or RA
- History of strictures or fistula (IBD)
- History of blood transfusion in the previous 6 months
- Pregnancy
- 6 months Postpartum
- Breastfeeding
- On other medications outside of FDA approved medications
- Current initiation of disease modifying or biologic medication within the past 2 months
- Unable to complete, for any reason, the initial 3-week run-in period prior to the beginning of the formal study intervention
- Non-English Speaking
- Organ failure of any kind including heart, liver and kidney failure or disease
- History of malignancy within the last year prior to enrollment
- Red meat allergy, alpha-gal allergy
The study team makes the final eligibility decision.
Where it is enrolling
- Charlottesville, Virginia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 64 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Charlottesville, Virginia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.