Recruiting at 25 sites Phase 2 Hypertension (HTN)

Hypertension study: QCZ484

Official title An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

ClinicalTrials.gov ID: NCT07543120

What this study is testing

What is QCZ484?

QCZ484 is an investigational injectable medicine being studied as a potential treatment for high blood pressure.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
This study is testing whether QCZ484 is safe and how well it works in people with high blood pressure who completed the earlier trial.
Who it's for
You may be able to join if you have high blood pressure and finished the earlier QCZ484 study.
What's involved
You will keep taking QCZ484 and have check‑ins to see safety and how well it works.
Time commitment
The study lasts several months with regular visits as scheduled.
  • Phase 2: a mid-size study of how well it works

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older

You may be able to join if

  • Signed informed consent must be obtained prior to participation in the study.
  • Successful completion of treatment period on QCZ484 study medication in parent study.
  • No significant safety issue that may place participant at safety risk as determined by the Investigator.

You likely can't join if

  • Evidence of hepatic disease that would put participant at risk by taking QCZ484 for long term as determined by the Investigator.
  • Clinically significant cardiac arrhythmias (e.g., ventricular tachycardia), high-grade atrioventricular (AV) block (e.g., Mobitz type II and...
  • Permanent or persistent atrial fibrillation developed during the parent study.
  • Clinically significant valvular heart disease developed during the parent study.
  • Acute myocardial infarction (AMI) or unstable angina, or any percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)...

The study team makes the final eligibility decision.

Where it is enrolling

  • Garden Grove, California, United States
  • Los Angeles, California, United States
  • Brandon, Florida, United States
  • Miami, Florida, United States
  • Miami Lakes, Florida, United States
  • Pembroke Pines, Florida, United States
  • Tampa, Florida, United States
  • Wellington, Florida, United States
  • Fayetteville, Georgia, United States
  • Chicago, Illinois, United States
  • Wichita, Kansas, United States
  • Ft. Washington, Maryland, United States
  • Troy, Michigan, United States
  • Jefferson City, Missouri, United States
  • Berlin, New Jersey, United States
  • Monroe, North Carolina, United States
  • Edmond, Oklahoma, United States
  • Memphis, Tennessee, United States
  • San Antonio, Texas, United States
  • Suita, Osaka, Japan

+ 4 more site(s).

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Garden Grove, California, United States; Los Angeles, California, United States; Brandon, Florida, United States; Miami, Florida, United States; Miami Lakes, Florida, United States; Pembroke Pines, Florida, United States and 18 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.