Acne Vulgaris study: Sarecycline vs Doxycycline
Official title Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
ClinicalTrials.gov ID: NCT07544251
What this study is testing
What is Sarecycline?
An investigational oral antibiotic being studied for acne vulgaris.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see how the gut and skin bacteria change when people with acne take either Sarecycline or Doxycycline.
- Who it's for
- It is looking for people who have acne vulgaris.
- What's involved
- Participants will receive either Sarecycline or Doxycycline and have their skin and gut bacteria examined before and after treatment.
- Time commitment
- The study lasts for the duration of the antibiotic course, with visits to collect samples at the start and end of treatment.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 9 and older. Healthy volunteers may be eligible.
You may be able to join if
- At least 10 inflammatory lesions (papules, pustules, and nodules) up to 100 noninflammatory lesions (open and closed comedones)
- No more than 2 nodules on the face
You likely can't join if
- Dermatological condition of face or facial hair that could interfere with clinical evaluations
- Topical acne medications such as retinoids, antibiotics, hormonal modulators
- Topical benzoyl peroxide
- Systemic antibiotics
- Systemic acne treatments
- Oral probiotic supplement
See the full eligibility criteria
- At least 10 inflammatory lesions (papules, pustules, and nodules) up to 100 noninflammatory lesions (open and closed comedones)
- No more than 2 nodules on the face
- Dermatological condition of face or facial hair that could interfere with clinical evaluations
- Topical acne medications such as retinoids, antibiotics, hormonal modulators
- Topical benzoyl peroxide
- Systemic antibiotics
- Systemic acne treatments
- Oral probiotic supplement
- Systemic retinoids 3) Individuals who have changed any of their hormonal based contraception or therapies within 3 months prior to joining the study. 4) Individuals who are pregnant or breastfeeding.
The study team makes the final eligibility decision.
Where it is enrolling
- Sacramento, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 9 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Sacramento, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.