Post-menopause study: DHEA ovals vs Estradiol
Official title VEDA Study (DHEA vs Estradiol)
ClinicalTrials.gov ID: NCT07574216
What this study is testing
What is DHEA ovals?
An investigational vaginal treatment being studied for post‑menopausal vaginal and urinary symptoms. It is designed to be converted by vaginal cells into small amounts of estrogen and androgens to support vaginal tissue health.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to see how these two treatments affect vaginal health and sexual function, so doctors can choose the best option.
- Who it's for
- Women who are post‑menopausal or pre‑menopausal and have vaginal dryness, painful intercourse, or urinary problems.
- What's involved
- Participants will use one of the two treatments for a set time, fill out symptom questionnaires, and have simple vaginal tests at the start and end.
- Time commitment
- The study lasts a few weeks to months, with regular visits for questionnaires and tests as scheduled.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 90, women only. Healthy volunteers may be eligible.
You may be able to join if
- Peri- or post-menopausal status
- Presence of any genitourinary or vaginal symptom (e.g., dryness, itching, discomfort, dyspareunia)
- Willingness and ability to use vaginal therapy
- Ability to provide informed consent
- English speaker
You likely can't join if
- Use of systemic hormone therapy within the last 6 months
- Gynecologic malignancy
- Known allergy to study medications
- Active vaginal infection at enrollment
- Prior pelvic radiation
See the full eligibility criteria
- Peri- or post-menopausal status
- Presence of any genitourinary or vaginal symptom (e.g., dryness, itching, discomfort, dyspareunia)
- Willingness and ability to use vaginal therapy
- Ability to provide informed consent
- English speaker
- Ages 40-90
- Use of systemic hormone therapy within the last 6 months
- Gynecologic malignancy
- Known allergy to study medications
- Active vaginal infection at enrollment
- Prior pelvic radiation
The study team makes the final eligibility decision.
Where it is enrolling
- Phoenix, Arizona, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 40 years to 90 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Phoenix, Arizona, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.