Neovascular (Wet) Age-Related Macular Degeneration study: EYC-0305
Official title Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration
ClinicalTrials.gov ID: NCT07587515
What this study is testing
What is EYC-0305?
EYC-0305 is an investigational injectable medicine being studied for wet age-related macular degeneration. It is designed to block a protein called VEGF that helps grow new, leaky blood vessels in the eye.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether a new eye injection is safe. It also looks at how well it works for your vision.
- Who it's for
- You may be able to join if you have wet age-related macular degeneration.
- What's involved
- You would get an injection in your eye. You would also have regular check-ups and vision tests.
- Time commitment
- You would get an injection every 24 weeks.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- Men or women 50 years and older with neovascular (wet) AMD meeting all study-specified eligibility criteria
- Willing and able to comply with clinic visits and study-related procedures
- Provide signed informed consent
You likely can't join if
- Known hypersensitivity or known allergy that would preclude study drug administration
- Inability to obtain ophthalmic imaging, eg, due to media opacity, inadequate pupillary dilation, allergy to fluorescein dye or lack of venous access
- Uncontrolled diabetes mellitus
- History of cerebrovascular accident (CVA) or myocardial infarction within 180 days of the Day 1 visit
- Renal failure, dialysis, or history of renal transplant
- Concurrent psychiatric or medical condition that in the opinion of the Investigator will interfere with study participation or completion
See the full eligibility criteria
- Men or women 50 years and older with neovascular (wet) AMD meeting all study-specified eligibility criteria
- Willing and able to comply with clinic visits and study-related procedures
- Provide signed informed consent
- Known hypersensitivity or known allergy that would preclude study drug administration
- Inability to obtain ophthalmic imaging, eg, due to media opacity, inadequate pupillary dilation, allergy to fluorescein dye or lack of venous access
- Uncontrolled diabetes mellitus
- History of cerebrovascular accident (CVA) or myocardial infarction within 180 days of the Day 1 visit
- Renal failure, dialysis, or history of renal transplant
- Concurrent psychiatric or medical condition that in the opinion of the Investigator will interfere with study participation or completion
- Pregnant or breastfeeding women
The study team makes the final eligibility decision.
Where it is enrolling
- Beverly Hills, California, United States
- Modesto, California, United States
- Wake Forest, North Carolina, United States
- Erie, Pennsylvania, United States
- Bellaire, Texas, United States
- McAllen, Texas, United States
- The Woodlands, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Beverly Hills, California, United States; Modesto, California, United States; Wake Forest, North Carolina, United States; Erie, Pennsylvania, United States; Bellaire, Texas, United States; McAllen, Texas, United States and 1 more location. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.