Dry Eye Syndrome study: Part
Official title Evaluation of a Novel Ocular Lubricating Eye Drop
ClinicalTrials.gov ID: NCT07593404
What this study is testing
What is ABR2?
An investigational ocular lubricating drop being studied for dry eye syndrome (DES).
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether the new eye drop ABR2 is safe and tolerable for short‑term use in people with dry eye.
- Who it's for
- You may be able to join if you have dry eye syndrome and are looking for temporary relief of eye discomfort.
- What's involved
- You will use one drop of ABR2 in one eye and have eye checks for one hour. Later, you will use one drop at least twice a day for 28 days, up to four times if needed.
- Time commitment
- The study lasts 28 days and includes an initial one‑hour visit and daily use of the eye drop at home.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Are at least 18 years of age and have capacity to volunteer
- Are able to read (Part 2 only);
- Have signed an information and consent letter;
- Are willing to follow instructions and maintain the appointment schedule;
- Are willing to refrain from contact lens wear throughout the study period;
You likely can't join if
- Participation in another ocular clinical research study or pharmaceutical clinical study within the past 14 days;
- Have a known active ocular disease and/ or infection with the exception of dry eye disease;
- Have any slit lamp findings that would contraindicate use of the study product;
- Have a systemic condition that would contraindicate use of the study product;
- Are using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
- Have undergone refractive error surgery or intraocular surgery within the last 12 months;
See the full eligibility criteria
- Are at least 18 years of age and have capacity to volunteer
- Are able to read (Part 2 only);
- Have signed an information and consent letter;
- Are willing to follow instructions and maintain the appointment schedule;
- Are willing to refrain from contact lens wear throughout the study period;
- Have a best corrected visual acuity of +0.20 LogMAR or better in each eye;
- Have an OSDI score ≥13 AND at least one of the following signs in at least one eye: Non-invasive tear film break-up time (NITBUT) \ 5 corneal spots, and/ or \> 9 conjunctival spots)
- Participation in another ocular clinical research study or pharmaceutical clinical study within the past 14 days;
- Have a known active ocular disease and/ or infection with the exception of dry eye disease;
- Have any slit lamp findings that would contraindicate use of the study product;
- Have a systemic condition that would contraindicate use of the study product;
- Are using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
- Have undergone refractive error surgery or intraocular surgery within the last 12 months;
- Have any known sensitivity or allergy to the diagnostic sodium fluorescein or to any ingredients in the study product;
- Are using ocular lubricating eye drops more than twice per day on a typical day over the past month (Part 2 only);
- Are an employee of the Centre for Ocular Research \& Education directly involved in this study
The study team makes the final eligibility decision.
Where it is enrolling
- Waterloo, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Waterloo, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.