Obesity study: PF-08653944
Official title A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
ClinicalTrials.gov ID: NCT07595549
What this study is testing
What is PF-08653944?
PF-08653944 is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for obesity.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to find out how well berobenatide works for weight loss and whether it is safe.
- Who it's for
- Adults who are overweight or have obesity, and may also have type 2 diabetes.
- What's involved
- Participants receive a daily injection under the belly skin of either berobenatide or a placebo, and attend regular clinic visits and phone calls for monitoring.
- Time commitment
- The study lasts about 20 months with roughly 15 in‑person visits and 2 phone visits.
- Phase 3: a large, late-stage study
- Time commitment: about 20 months
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged ≥18 years.
- BMI of: ≥30 kg/m2 or ≥27.0 kg/m2 to \<30.0 kg/m2 and must have at least 1 of the following weight-related co-morbidities: hypertension, dyslipidemia...
You likely can't join if
- Have a self-reported body weight change greater than 5% within 90 days prior to Screening.
- Diagnosis of type 1 diabetes or any other form of diabetes other than T2D.
- History of acute or chronic pancreatitis.
- Personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN-2).
The study team makes the final eligibility decision.
Where it is enrolling
- Canoga Park, California, United States
- Escondido, California, United States
- Modesto, California, United States
- Sacramento, California, United States
- Tustin, California, United States
- Walnut Creek, California, United States
- West Hills, California, United States
- Crystal River, Florida, United States
- Lecanto, Florida, United States
- Miramar, Florida, United States
- Pembroke Pines, Florida, United States
- Chicago, Illinois, United States
- Evanston, Illinois, United States
- Skokie, Illinois, United States
- Evansville, Indiana, United States
- Baltimore, Maryland, United States
- Flint, Michigan, United States
- Omaha, Nebraska, United States
- Albuquerque, New Mexico, United States
- New York, New York, United States
+ 46 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 20 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Canoga Park, California, United States; Escondido, California, United States; Modesto, California, United States; Sacramento, California, United States; Tustin, California, United States; Walnut Creek, California, United States and 60 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.