Major Depressive Disorder study: DT-101
Official title A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
ClinicalTrials.gov ID: NCT07610473
What this study is testing
What is DT-101?
DT-101 is an investigational oral medication being studied for the treatment of Major Depressive Disorder (MDD).
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether DT-101 can improve depression symptoms compared to a pretend treatment. It looks at how well the drug works and how safe it is.
- Who it's for
- You may be able to join if you are an adult with major depression and can travel to the clinic for visits.
- What's involved
- You will take DT-101 or a pretend treatment and go to the clinic for health checks and questionnaires. The visits will include talking with the study team and filling out forms.
- Time commitment
- The study lasts several weeks, with multiple clinic visits for health checks and questionnaires.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- The participant is able to read, understand and communicate in the local language used at the study site, and is willing to provide written informed...
- Male or female (assigned at birth, inclusive of all gender identities) participant must be 18 to 75 years of age, inclusive at the time of signing...
- Has recurrent depression (defined as at least one prior episode excluding the current one), as diagnosed by DSM 5-TR (Diagnostic and Statistical...
You likely can't join if
- Pregnant or breastfeeding or plans to become pregnant during the study.
- Unstable medical condition or unstable chronic disease.
- Significant neurological abnormality.
- History of moderate or severe alcohol or drug use disorder as per DSM-5-TR in the 6 months prior to Screening.
- History of seizure.
- In the investigator's opinion, the participant is not capable of adhering to the protocol requirements.
The study team makes the final eligibility decision.
Where it is enrolling
- Phoenix, Arizona, United States
- Little Rock, Arkansas, United States
- Bellflower, California, United States
- Costa Mesa, California, United States
- Lafayette, California, United States
- Hialeah, Florida, United States
- Orlando, Florida, United States
- Tampa, Florida, United States
- Decatur, Georgia, United States
- Chicago, Illinois, United States
- Skokie, Illinois, United States
- Boston, Massachusetts, United States
- New York, New York, United States
- Columbus, Ohio, United States
- Allentown, Pennsylvania, United States
- Media, Pennsylvania, United States
- DeSoto, Texas, United States
- Fort Worth, Texas, United States
- Bellevue, Washington, United States
- Seattle, Washington, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Phoenix, Arizona, United States; Little Rock, Arkansas, United States; Bellflower, California, United States; Costa Mesa, California, United States; Lafayette, California, United States; Hialeah, Florida, United States and 14 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.