Hypercholesterolaemia study: Laroprovstat/rosuvastatin vs Rosuvastatin
Official title A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia
ClinicalTrials.gov ID: NCT07619118
What this study is testing
What is laroprovstat/rosuvastatin 1?
an investigational oral combination medicine being studied for hypercholesterolaemia.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether a fixed‑dose combo of laroprovstat and rosuvastatin lowers LDL‑C and is safe compared with rosuvastatin alone.
- Who it's for
- You may be able to join if you have high cholesterol and either have had a heart‑related event or are at risk for one.
- What's involved
- You would take a daily pill that contains both drugs, or a daily pill with only rosuvastatin. You will have blood tests to check cholesterol and safety.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 130
You may be able to join if
- Participant must be ≥ 18 years of age
- Participants must be on a stable dose of all background LLTs
- The stable statin dose should be judged as their maximally tolerated dose
- Participants should have either history of a clinical ASCVD event or be at increased risk for a first clinical ASCVD event
You likely can't join if
- Asian origin
- Uncontrolled severe hypertension
- Uncontrolled T2DM
- Inadequately treated hypothyroidism
The study team makes the final eligibility decision.
Where it is enrolling
- Sun City West, Arizona, United States
- Pomona, California, United States
- Miami Lakes, Florida, United States
- Conyers, Georgia, United States
- Decatur, Georgia, United States
- Beltsville, Maryland, United States
- Houston, Texas, United States
- Mesquite, Texas, United States
- Sugar Land, Texas, United States
- Hope Island, Australia
- Woolloongabba, Australia
- Guelph, Ontario, Canada
- Mississauga, Ontario, Canada
- North York, Ontario, Canada
- Stoney Creek, Ontario, Canada
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 130 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Sun City West, Arizona, United States; Pomona, California, United States; Miami Lakes, Florida, United States; Conyers, Georgia, United States; Decatur, Georgia, United States; Beltsville, Maryland, United States and 10 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.