Obesity study: ALN-6222
Official title A Study to Evaluate ALN-6222 in Participants With Obesity
ClinicalTrials.gov ID: NCT07624071
What this study is testing
What is ALN-6222?
An investigational once‑daily injectable medicine being studied for obesity.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study will look at how safe and well the drug is tolerated, how it moves through the body, and whether it shows any signs of helping with obesity.
- Who it's for
- Adults who have obesity and are willing to participate in a clinical trial.
- What's involved
- Participants will receive injections of the drug or a placebo, and will have blood tests and other safety checks during the study.
- Time commitment
- The study lasts a few weeks, with several clinic visits for injections and monitoring.
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Is an adult patient with a body mass index ≥30 kg/m\^2 to \<40 kg/m\^2
- Has a hemoglobin A1c \<6.5%
You likely can't join if
- Has alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>1.5 times the upper limit of normal (ULN)
- Has known human immunodeficiency virus (HIV) infection; or known current or chronic hepatitis C virus or hepatitis B virus infection
- Has an estimated glomerular filtration (eGFR) of \<60 mL/min/1.73m\^2 at screening Note: other protocol defined inclusion / exclusion criteria apply
The study team makes the final eligibility decision.
Where it is enrolling
- Mount Royal, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Mount Royal, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.