Clinical trial for Subcortical Lesions
Official title Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke
ClinicalTrials.gov ID: NCT07663292
What this study is testing
- What it's testing
- The study wants to find brain markers that predict who will improve or not with high‑intensity interval training (HIIT).
- Who it's for
- Adults who had a stroke long ago and now have trouble walking because of lower‑limb weakness.
- What's involved
- Participants will cycle 3 times a week for 25‑60 minutes, sometimes giving a finger‑prick blood sample. They will have brain MRIs and motor tests before and after the program, and answer health and diet questionnaires.
- Time commitment
- The program lasts 14‑16 weeks with up to 42 visits, including exercise sessions, scans, and tests.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- chronic left or right subcortical stroke as defined by 6 months or more after a cardiovascular accident
- lower extremity motor impairment due to stroke that causes a walking speed of less than 0.6 m/s during a 10m walk,
- age 18-80 years old, and
- Screen pass of the Stress test or Physician sign-off from the participant's health care team that they are cleared for a 12 week exercise intervention
You likely can't join if
- MRI contraindications, including implanted cardiac pacemakers and severe claustrophobia
- any neurodegenerative condition other than stroke that may lead to lower extremity impairment
- visual or auditory impairment that may hinder study procedures, and
- any medical condition that would preclude from participation in a physical exercise intervention program.
The study team makes the final eligibility decision.
Where it is enrolling
- Atlanta, Georgia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Atlanta, Georgia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.