Clinical trial for Alzheimer s Disease
Official title NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
ClinicalTrials.gov ID: NCT07667478
What this study is testing
- What it's testing
- The study wants to know if repetitive transcranial magnetic stimulation can improve short‑term memory and is safe for people with early Alzheimer’s. It also looks at how the brain’s activity changes with MRI scans.
- Who it's for
- Adults who have early Alzheimer’s disease, mild cognitive impairment due to Alzheimer’s, or mild dementia.
- What's involved
- Participants are randomly assigned to real or fake (sham) brain stimulation, receive 20 sessions of rTMS over four weeks, have two MRI scans (before and after), and complete memory and thinking tests at several time points.
- Time commitment
- The study lasts about six months, including a screening visit, daily treatment sessions for four weeks, and follow‑up visits at the end of treatment, three months, and six months.
- Time commitment: about 4 weeks
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 55 to 90
You may be able to join if
- A clinical diagnosis of early AD, defined as either mild cognitive impairment (MCI) due to AD or mild dementia due to AD;
- Evidence of cognitive impairment, characterized by a MMSE score between 20 and 28 and/or a CDR-Sum of Boxes score between 0.5 and 8, consistent with...
- Biomarker confirmation of AD pathology, demonstrated by a positive plasma phosphorylated tau-217 (p-tau217) result according to the 2024 National...
You likely can't join if
- Exclusion criteria include evidence of other neurological, psychiatric, or systemic conditions that could cause cognitive and functional impairments...
- Individuals who have contraindications to receiving rTMS, including a history of seizures or any non-removable metal in their heads or within 12...
The study team makes the final eligibility decision.
Where it is enrolling
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 4 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 55 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Houston, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.