Overweight study: Zenagamtide vs Semaglutide
Official title A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
ClinicalTrials.gov ID: NCT07668414
What this study is testing
What is Zenagamtide?
an investigational injectable medicine being studied as a potential treatment for overweight individuals
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to find out whether Zenagamtide is safe and works as well as Semaglutide for people with excess body weight.
- Who it's for
- Adults who are overweight or have obesity.
- What's involved
- Participants will be given either Zenagamtide or Semaglutide and will have regular check‑ups and tests to monitor safety and weight changes.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male or female (sex at birth).
- Age 18 years or above at the time of signing the informed consent.
You likely can't join if
- Glycated haemoglobin (HbA1c) ≥ 6.5% (48 millimoles per mole [mmol/mol]) as measured by the central laboratory at screening.
- History of type 1 or type 2 diabetes mellitus as declared by the participant or reported in the medical records.
- Treatment with glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based...
The study team makes the final eligibility decision.
Where it is enrolling
- Lancaster, California, United States
- Palm Springs, California, United States
- Pomona, California, United States
- San Diego, California, United States
- Washington D.C., District of Columbia, United States
- Hollywood, Florida, United States
- Miami, Florida, United States
- Miramar, Florida, United States
- Orlando, Florida, United States
- Oviedo, Florida, United States
- West Palm Beach, Florida, United States
- Weston, Florida, United States
- Atlanta, Georgia, United States
- Snellville, Georgia, United States
- Skokie, Illinois, United States
- Indianapolis, Indiana, United States
- St Louis, Missouri, United States
- Syracuse, New York, United States
- West Seneca, New York, United States
- Statesville, North Carolina, United States
+ 12 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Lancaster, California, United States; Palm Springs, California, United States; Pomona, California, United States; San Diego, California, United States; Washington D.C., District of Columbia, United States; Hollywood, Florida, United States and 26 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.