Upper Limb Essential Tremor study: AGN-151607-DP
Official title Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor
ClinicalTrials.gov ID: NCT07673107
What this study is testing
What is AGN-151607-DP?
an investigational intramuscular injectable medicine being studied as a potential treatment for upper‑limb essential tremor
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether AGN-151607-DP is safe and works to reduce tremor in adults with upper limb essential tremor.
- Who it's for
- You may be able to join if you are an adult with upper limb essential tremor.
- What's involved
- You would get a muscle injection of either AGN-151607-DP or a pretend treatment with no medicine. You will fill out questionnaires and have medical check‑ups to track side effects.
- Time commitment
- The study lasts about 72 weeks with regular visits for injections and assessments.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Minimum body weight of 50 kg (110 pounds) at Screening.
- Bilateral postural tremor with or without kinetic tremor, involving hands and forearms
- Tremor of other body parts may or may not be present in addition to upper limb (UL) tremor
- Bilateral tremor may or may not be asymmetric
- Tremor that is reported by the participant to be persistent, although the amplitude may fluctuate.
You likely can't join if
- History of any medical condition that may put the participant at increased risk with exposure to purified botulinum toxin type A complex, including...
- History of an allergic reaction to or significant sensitivity to AGN-151607-DP or its excipients and/or other botulinum toxins.
The study team makes the final eligibility decision.
Where it is enrolling
- Carlsbad, California, United States
- Fresno, California, United States
- Fullerton, California, United States
- Stamford, Connecticut, United States
- Boca Raton, Florida, United States
- Orlando, Florida, United States
- Pensacola, Florida, United States
- Overland Park, Kansas, United States
- Amherst, New York, United States
- Commack, New York, United States
- Winston-Salem, North Carolina, United States
- New Albany, Ohio, United States
- Memphis, Tennessee, United States
- Dallas, Texas, United States
- Frisco, Texas, United States
- Houston, Texas, United States
- Charlottesville, Virginia, United States
- Spokane, Washington, United States
- Greenfield, Wisconsin, United States
- Lévis, Quebec, Canada
+ 1 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Carlsbad, California, United States; Fresno, California, United States; Fullerton, California, United States; Stamford, Connecticut, United States; Boca Raton, Florida, United States; Orlando, Florida, United States and 15 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.