Clinical trial for Stroke, Acute Ischemic
Official title ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632
ClinicalTrials.gov ID: NCT07687056
What this study is testing
What is Tenecteplase or Alteplase?
This is an investigational treatment being studied to see if it helps people with acute ischemic stroke after a specific procedure. It is designed to dissolve blood clots in the brain's arteries.
Also referred to as tNKase, Metalyse, tPA, Activase.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether adding a clot-busting drug during surgery works better than standard care alone. It looks at how well people recover after an ischemic stroke.
- Who it's for
- You may be able to join if you have an ischemic stroke and are having a surgery to remove a blood clot.
- What's involved
- You would be picked by chance to get a clot-busting drug during your surgery. Some people would only get the standard surgery care.
- Time commitment
- The study lasts 90 days, and you will have check-ins to see how you are doing.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥18 years
- Clinical diagnosis of stroke
You likely can't join if
- There are no platform level exclusion criteria.
The study team makes the final eligibility decision.
Where it is enrolling
- Calgary, Alberta, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Calgary, Alberta, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.