Trial comparing treatments for Renal Cell Carcinoma (RCC)
Official title Comparing Two Weight Loss Programs for the Prevention of Kidney Cancer Progression Among Patients With Small Renal Masses on Active Surveillance
ClinicalTrials.gov ID: NCT07714018
What this study is testing
- What it's testing
- This clinical trial compares two different weight-loss programs, daily continuous calorie energy reduction (CER) versus (vs.) 5:2 intermittent fasting (IF), in preventing progression of kidney (renal) cancer among patients with one or more small renal masses (SRM) undergoing active surveillance (AS). Kidney cancer patients tend to have changes in metabolism that may increase body weight, but weight-loss strategies that work for best for these patients are unknown.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- English speaking
- SRM patient with biopsy-confirmed RCC who are initiating or already on AS
- Age 18 years or older
- Body mass index (BMI) ≥ 25 kg/m\^2
- No medical problems that might contraindicate participation in a behavioral weight reduction program containing an exercise component
You likely can't join if
- Non-English speaking
- Less than 18 years old
- BMI \< 25 kg/m\^2
- Medical problems that might contraindicate participation in a behavioral weight reduction program containing an exercise component
- On weight loss medication in the past 3 months
- Pregnant or lactating
See the full eligibility criteria
- English speaking
- SRM patient with biopsy-confirmed RCC who are initiating or already on AS
- Age 18 years or older
- Body mass index (BMI) ≥ 25 kg/m\^2
- No medical problems that might contraindicate participation in a behavioral weight reduction program containing an exercise component
- No weight loss medication in the past 3 months
- Not pregnant or lactating
- No more than 5% body weight loss in the past 3 months
- No bariatric surgery in the last 10 years
- Non-English speaking
- Less than 18 years old
- BMI \< 25 kg/m\^2
- Medical problems that might contraindicate participation in a behavioral weight reduction program containing an exercise component
- On weight loss medication in the past 3 months
- Pregnant or lactating
- More than 5% body weight loss in the past 3 months
- Bariatric surgery in the last 10 years
- Any condition which in the Investigator's opinion deems the participant an unsuitable candidate to receive study drug
- Unwilling or unable to follow protocol requirements
- Received an investigational agent within 30 days prior to enrollment
The study team makes the final eligibility decision.
Where it's taking place
- Buffalo, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Buffalo, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.