Recruiting at 1 site Phase 4 Obesity & Overweight

Obesity & Overweight study: Semaglutide vs Wegovy®

Official title A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity

ClinicalTrials.gov ID: NCT07728383

What this study is testing

What is Semaglutide 6 mg liquid emulsion formulation?

An investigational oral liquid formulation of semaglutide being studied for weight loss in people who are overweight or obese. It is designed to activate GLP‑1 receptors to help reduce appetite.

Also referred to as Semaglutide.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
This study is testing whether a mouth spray of semaglutide can help people with obesity feel fuller and lose weight.
Who it's for
You may be able to join if you are an adult who is overweight or obese.
What's involved
You would use a small liquid spray in your mouth for a few minutes each day. The study will check how you feel and measure your weight and health.
  • Phase 4: studies an already-approved treatment
  • You might receive a placebo (an inactive treatment) instead of the study drug.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 65

You may be able to join if

  • Body Mass Index 30 to 45

You likely can't join if

  • Type 2 Diabetes Mellitus
  • Multiple Endocrine Neoplasia Type 2
  • Medullary thyroid cancer

The study team makes the final eligibility decision.

Where it is enrolling

  • Minneapolis, Minnesota, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Minneapolis, Minnesota, United States. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.