Hypertension study: Isometric Wall Squat
Official title How Wall Squat Exercise Affects Blood Pressure in People With High Blood Pressure and Treated Sleep Apnea (WALLPRESS)
ClinicalTrials.gov ID: NCT07730879
What this study is testing
- What it's testing
- The study aims to find out if doing a specific wall squat exercise lowers blood pressure more than resting does.
- Who it's for
- Adults who have high blood pressure and obstructive sleep apnea that is treated with a CPAP machine.
- What's involved
- Participants will do one session of wall squats and one rest session at home. They will wear a monitor to track their blood pressure for 12 hours after each session.
- Time commitment
- The study takes about one week, requiring a familiarization visit and two home sessions spaced at least two days apart.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- 18-80 years old.
- Diagnosis of hypertension and OSA confirmed by polysomnography or respiratory sleep study.
- Apnea-Hypopnea Index (AHI) of at least 15 events per hour.
- Treatment with CPAP for at least 3 months.
You likely can't join if
- Mean CPAP adherence \<4 hours/night over the last month, documented by device download.
- Heart failure.
- Peripheral artery disease.
- Atrial fibrillation.
- Chronic obstructive pulmonary disease.
- Chronic kidney disease.
See the full eligibility criteria
- 18-80 years old.
- Diagnosis of hypertension and OSA confirmed by polysomnography or respiratory sleep study.
- Apnea-Hypopnea Index (AHI) of at least 15 events per hour.
- Treatment with CPAP for at least 3 months.
- Mean CPAP adherence \<4 hours/night over the last month, documented by device download.
- Heart failure.
- Peripheral artery disease.
- Atrial fibrillation.
- Chronic obstructive pulmonary disease.
- Chronic kidney disease.
- History of acute coronary syndrome, stroke, or transient ischemic attack in the previous 12 months.
- Relevant changes in antihypertensive or other cardiovascular pharmacotherapy in the previous 3 months.
- Relevant changes in CPAP prescription in the previous 3 months.
- Any contraindication to exercise according to contemporary ESC/ACSM recommendations (e.g. unstable angina).
- Pregnancy or breastfeeding.
- Neurological and/or orthopaedic conditions that could interfere with exercise (e.g. severe knee osteoarthritis, recent lower-limb surgery).
- Inability to read, understand, or provide informed consent.
The study team makes the final eligibility decision.
Where it is enrolling
- Braga, Portugal
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Braga, Portugal. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.