Dihydrotestosterone study: Finasteride
Official title Finasteride and Cutibacterium
ClinicalTrials.gov ID: NCT07731802
What this study is testing
What is Finasteride 5 mg?
Finasteride 5 mg is an investigational medicine, taken by mouth once daily, being studied as a potential treatment for dihydrotestosterone.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- High levels of Testosterone causes high amounts of skin bacteria (Cutibacterium Acnes) which can go into the skin during a shoulder replacement surgery and cause a terrible infection.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65, men only. Healthy volunteers may be eligible.
You may be able to join if
- Inclusion We will include the group most impacted by PJI
- Adult males
- Age between 18 and 65 Exclusion
- History of cryptorchidism, hypospadias, or other congenital abnormality of male reproductive tract
- Female sex
See the full eligibility criteria
- Inclusion We will include the group most impacted by PJI
- Adult males
- Age between 18 and 65 Exclusion
- History of cryptorchidism, hypospadias, or other congenital abnormality of male reproductive tract
- Female sex
- Age younger than 18 or older than 65
- Current use of Finasteride or other 5-alpha reductase inhibitors
- Current use of hormone replacement medications such as testosterone
- Recent antibiotic use within 3 months
- Have had a negative reaction to oral Finasteride before
- Recent use of acne treatment within 3 months
- Self-report very sensitive skin
- Allergic to chlorhexidine or isopropyl alcohol
- Have open wounds on both shoulders
The study team makes the final eligibility decision.
Where it is enrolling
- Seattle, Washington, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Seattle, Washington, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.