Clinical trial for Parkinson Disease
Official title Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
ClinicalTrials.gov ID: NCT07748962
What this study is testing
- What it's testing
- The study aims to understand how brain signals relate to balance issues and sudden stops in walking. It also looks at how different settings for a brain implant might change these symptoms.
- Who it's for
- People with Parkinson's disease who have trouble with balance or freezing while walking.
- What's involved
- Participants will have their brain signals recorded while walking. Researchers will also adjust the settings of their deep brain stimulation device to see how it affects their symptoms.
- Time commitment
- The source text does not specify the duration or number of visits required.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- You have been diagnosed with Parkinson's disease
- You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device
- Your DBS settings have been stable for at least 3 months
- You experience freezing of gait (sudden inability to move your feet when trying to walk)
- You are able to walk on your own for at least 10 minutes without assistance
You likely can't join if
- You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis)
- You have been diagnosed with dementia or have difficulty understanding the study or giving consent
- You currently have alcohol or substance abuse problems
- You have hearing or vision problems that would make it difficult to use a virtual reality headset
- You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate
See the full eligibility criteria
- You have been diagnosed with Parkinson's disease
- You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device
- Your DBS settings have been stable for at least 3 months
- You experience freezing of gait (sudden inability to move your feet when trying to walk)
- You are able to walk on your own for at least 10 minutes without assistance
- You are willing to temporarily stop your Parkinson's medications and have your DBS settings adjusted for study testing
- You are able to understand the study and provide consent to participate
- You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis)
- You have been diagnosed with dementia or have difficulty understanding the study or giving consent
- You currently have alcohol or substance abuse problems
- You have hearing or vision problems that would make it difficult to use a virtual reality headset
- You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate
The study team makes the final eligibility decision.
Where it is enrolling
- Cleveland, Ohio, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Cleveland, Ohio, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.