Acute Pancreatitis study: Lactated Ringer's
Official title Stroke Volume-based Fluid Resuscitation in AP
ClinicalTrials.gov ID: NCT07756476
What this study is testing
- What it's testing
- The study compares a stroke‑volume‑guided fluid plan with the usual aggressive hydration to see if it reduces fluid overload and improves outcomes.
- Who it's for
- Adults hospitalized with acute pancreatitis who can receive IV fluids.
- What's involved
- Participants will receive IV fluids guided by their stroke volume measurements, with regular monitoring and blood tests during their hospital stay.
- Time commitment
- The trial lasts for the duration of the hospital stay, with daily assessments and follow‑up visits as needed.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Patients between the age of 18-75
- Predicted moderate and severe acute pancreatitis, which will be defined by the presence of SIRs, within 24 hours of enrollment
You likely can't join if
- Patients with the inability to preform a straight leg raise (i.e amputation)
- Patients with high risk of adverse event related to fluid resuscitation
- NYHA Class \>= II Heart Failure
- Child's B and C Cirrhosis
- Dialysis Requirement
- Clinical signs of hypervolemia, including pulmonary congestion (i.e dyspnea, pulmonary crackles on exam, interstitual edema on imaging) and ascites
See the full eligibility criteria
- Patients between the age of 18-75
- Predicted moderate and severe acute pancreatitis, which will be defined by the presence of SIRs, within 24 hours of enrollment
- Patients with the inability to preform a straight leg raise (i.e amputation)
- Patients with high risk of adverse event related to fluid resuscitation
- NYHA Class \>= II Heart Failure
- Child's B and C Cirrhosis
- Dialysis Requirement
- Clinical signs of hypervolemia, including pulmonary congestion (i.e dyspnea, pulmonary crackles on exam, interstitual edema on imaging) and ascites
- Ages \<18 years old
- Pregnant
- Incarcerated
- Unable to provide informed consent
The study team makes the final eligibility decision.
Where it is enrolling
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Los Angeles, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.