Trial studying safety and effects for Back Pain Lower Back
Official title Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)
ClinicalTrials.gov ID: NCT07762170
What this study is testing
What is triamcinolone acetonide (Kenalog)?
triamcinolone acetonide (Kenalog) is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for back pain lower back.
Also referred to as epidural steroid injections, interlaminar steroid injections.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between injections with steroids and local anesthetics, to optimize this treatment that is currently not standardized. The investigators will compare retrospectively and prospectively the efficacy of different injections in the same patients, using mainly a parameter called integral of pain relief, which combines the percentage of pain relief provided by a treatment and its duration over time, as well as improvements in functionality.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- \>18 years of age;
- Diagnosis of lumbar, cervical, or thoracic pain with various etiologies;
- Eligibility to receive steroid injections for back pain, including epidural, facet joints, or SIJ injections, or other injections (e.g., local...
- Being willing and able to provide NRS pain ratings and PROMIS functionality ratings before the intervention, and the same scores plus IPR, fIPR, and...
- Provide written informed consent.
You likely can't join if
- Diagnosis of dementia, Parkinson's disease or other cognitive impairments;
- Congenital or acquired polyneuropathy;
- Back surgery in the month before injection treatment or planned surgery in the subsequent 3 months;
- Any clinically significant acute or chronic medical condition that in the judgment of Investigator may preclude injection in the epidural space or...
- Participation in any other competing clinical study within 3 months prior to screening and during the study period.
The study team makes the final eligibility decision.
Where it's taking place
- Thornhill, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Thornhill, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.