Chronic Low-back Pain study: Palmitoylethanolamide
Official title Palmitoylethanolamide Modulates Central Sensitisation and Neuroinflammation in Chronic Low Back Pain
ClinicalTrials.gov ID: NCT07772141
What this study is testing
What is Palmitoylethanolamide?
This is an investigational supplement being studied to see if it helps with chronic low back pain. It is designed to help reduce inflammation and pain signals in the body.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see if the treatment can reduce pain and improve quality of life for people with long‑term low back pain.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- With chronic pain (more than 3 months)
- Patients with NRS (4 -7)
- MRI evidence of disc protrusion or prolapse limited to one or two lumbar discs, without extensive multi-level pathology
- Diagnosed clinically with low back pain due to disc disease.
- ASA I and ASA II
You likely can't join if
- Neurological disorders
- psychiatric illness
- pregnancy
- prior spinal surgery
- concurrent use of immunomodulatory drugs
- contraindications to TMS.
See the full eligibility criteria
- With chronic pain (more than 3 months)
- Patients with NRS (4 -7)
- MRI evidence of disc protrusion or prolapse limited to one or two lumbar discs, without extensive multi-level pathology
- Diagnosed clinically with low back pain due to disc disease.
- ASA I and ASA II
- Neurological disorders
- psychiatric illness
- pregnancy
- prior spinal surgery
- concurrent use of immunomodulatory drugs
- contraindications to TMS.
- Allergy to the drug
The study team makes the final eligibility decision.
Where it is enrolling
- Banī Suwayf, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Banī Suwayf, Egypt. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.